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	Provedor de dados BJMBR (2) Autor Ibañez,O.M. (2) Barros,R.T. (1) Cabrera,W.H. (1) Domingues,W.V. (1) Flangini,M. (1) Kurihara,R.S. (1) Malheiros,D.A. (1) Martins,G.A. (1) Ribeiro,O.G. (1) Rizzo,L.V. (1) Sant'Anna,O.A. (1) Vieira de Moraes,L. (1) Yokoo,M. (1) de Almeida Prado,E.B. (1) Mais... Palavra-chave Acute inflammatory response (1) Autoimmunity (1) Chemokine (1) Genetically selected mice (1) Glomerulonephritis (1) IgA (1) IgG1 and IgG2a isotypes (1) Inflammation (1) Monocyte chemoattractant protein-1 (1) Uveitis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2006 (1) 2005 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última The anti-IRBP IgG1 and IgG2a response does not correlate with susceptibility to experimental autoimmune uveitis BJMBR Vieira de Moraes,L.; Martins,G.A.; Flangini,M.; Ibañez,O.M.; Sant'Anna,O.A.; Rizzo,L.V.. Susceptibility to experimental autoimmune uveitis (EAU) in inbred mice has been associated with a dominant Th1 response. Elevated anti-inter-photoreceptor retinoid-binding protein (anti-IRBP) IgG2a/IgG1 antibody ratios have been implicated as candidate markers to predict disease severity. In the present study, both the anti-IRBP antibody isotype and severity of EAU phenotypes were examined in 4 non-isogenic genetically selected mouse lines to determine if they can be used as general markers of disease. Mice between 8 and 12 weeks old selected for high (H III) or low (L III) antibody response and for maximum (AIR MAX) or minimum (AIR MIN) acute inflammatory reaction (AIR) were immunized with IRBP. Each experiment was performed with at least 5 mice per... Tipo: Info:eu-repo/semantics/article Palavras-chave: Autoimmunity; IgG1 and IgG2a isotypes; Inflammation; Genetically selected mice; Uveitis. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600010 Genetic potential for an acute inflammatory response in IgA glomerulonephritis in mice BJMBR Kurihara,R.S.; Yokoo,M.; Domingues,W.V.; Cabrera,W.H.; Ribeiro,O.G.; Ibañez,O.M.; Malheiros,D.A.; Barros,R.T.; de Almeida Prado,E.B.. Mice selected on the basis of an acute inflammatory response (AIR) can provide information about the immunopathological mechanisms of glomerulonephritis. We studied the differences between mice selected for a maximal AIR (AIRmax that attract more polymorphonuclear cells to the site of injury) or a minimal AIR (AIRmin that attract more mononuclear cells) in an experimental model of IgA nephropathy in order to investigate the effect of genetic background on glomerular disease progression and the participation of the monocyte chemoattractant protein-1 (MCP-1) chemokine. IgA nephropathy was induced by intraperitoneal ovalbumin injection and bile duct ligation in AIRmax and AIRmin mice. Histological changes, urinary protein/creatinine ratio, serum IgA levels,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Monocyte chemoattractant protein-1; IgA; Glomerulonephritis; Acute inflammatory response; Chemokine. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001200009 Registros recuperados: 2 Primeira ... 1 ... Última

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