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Irnidayanti,Yulia; Darmanto,Win. |
One of the plastic base material, widely used in the plastics industry in various countries, is a ester phthalate. These compounds will be oxidizedin the body to 2-methoxyethanol (2-ME). Effect of 2-ME on human health and the environment depends on the number, duration and frequency of exposure. 2-ME and its metabolites in the body can damage cells and tissues. The body can be exposed by 2-ME through the air, water and soil. Western blot results showed that the protein Vimentin was detectable in the control group at GD-11 to 17, meanwhile GFAP protein was detachable in the control group atGD- 12 to GD-18. After administration 2-ME, the expression of Vimentinprotein were changed, and started at GD- 12 up to GD-18. whereas the expression of GFAP protein... |
Tipo: Journal article |
Palavras-chave: 2-methoxyethanol; Vimentin; GFAP; Cerebral cortex; Brain. |
Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000300003 |
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Irnidayanti,Yulia. |
Zearalenonesolution was given to dams micesubcutaneouslyat a dose of30 mg/kg body weightat the age ofpregnancy 13 to 18 days.Control micewere given only sesameoil. Furthermore, damsmice were allowed todeliver their litter and pups were weanedon 21 days of age. The live birth index andviability of the F-1 offspring were recorded. Determination of fertility of the F-1 offspring were undertaken by mating interlitters. On days 18 of gestation, the F-1 offspring were killed by cervical dislocation. The observation was performed on the number of live or dead fetus, embryo resorption, the number of implantation and the percentage of gestation loss. The result revealed that administration of zearalenone on days 13 to 18 of gestation caused a significant decreasein... |
Tipo: Journal article |
Palavras-chave: Zearalenone; Fertilitas indeks; Gestation indeks; Number of implantation; Persistent. |
Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000300068 |
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