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	Provedor de dados International Journal of Morphology (3) Autor Jahanshahi,M (3) Azami,N. S (2) Babakordi,F (1) Khoshbin khoshnazar,A. R (1) Moharreri,A (1) Nickmahzar,E (1) Nickmahzar,E. G (1) Seif-hoseini,S (1) Mais... Palavra-chave Hippocampus (3) Rat (2) Scopolamine (2) Amnesia (1) Astrocyte (1) Avoidance memory (1) Fractionation (1) M1 receptor (1) Neurogenesis (1) Radiation (1) Mais... Tipo do documento Journal article (3) Ano 2013 (1) 2012 (2) País Chile (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Effect of Scopolamine-based Amnesia on the Number of Astrocytes in the Rat's Hippocampus International Journal of Morphology Jahanshahi,M; Azami,N. S; Nickmahzar,E. As neuron­astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms. In this study, the effect of scopolamine based amnesia on the number of astrocytes in rats' hippocampus was studied. Adult male albino Wistar rats were bilaterally cannulated into the CA1 region and animals received saline or different doses of scopolamine (0.5, 1 and 2 mg/ rat, intra - CA1), immediately after training. Then all the rats were sacrificed and coronal sections were taken from the dorsal hippocampal formation of the right cerebral hemispheres and stained with PTAH. The area densities of the astrocytes in dentate gyrus were measured and compared in the all groups (p < 0.05). Data... Tipo: Journal article Palavras-chave: Scopolamine; Amnesia; Astrocyte; Hippocampus; Rat. Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200004 Gamma Radiation-induced Impairment of Hippocampal Neurogenesis,Comparison of Single and Fractionated Dose Regimens International Journal of Morphology Khoshbin khoshnazar,A. R; Jahanshahi,M; Azami,N. S. Radiation therapy of the brain is associated with many consequences, including cognitive disorders. Pathogenesis of radiation induced cognitive disorder is not clear, but reduction of neurogenesis in hippocampus may be an underlying reason. 24 adult male rats entered to study. Radiation absorbed dose to midbrain was 10 Gy, delivered by routine cobalt radiotherapy machine which its output was measured 115.24 cGy/min. The rats were divided in four groups of sixes, including groups of control, single fraction 10 Gy, fractionated 10 Gy and finally anaesthesia sham group. Number of pyramidal nerve cells was counted in two regions of hippocampus formation (CA1 and CA3). The radiation could reduce the number of cells in two regions of hippocampus significantly... Tipo: Journal article Palavras-chave: Hippocampus; Neurogenesis; Radiation; Fractionation. Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100026 Scopolamine Reduces the Density of M1 Muscarinic Neurons in Rats' Hippocampus International Journal of Morphology Jahanshahi,M; Nickmahzar,E. G; Seif-hoseini,S; Babakordi,F; Moharreri,A. Cholinergic system in CNS is involved in learning and memory. Scopolamine as muscarinic acetylcholine receptor antagonist is used for creation of memory impairment. The purpose of this study is evaluation of scopolamine-based amnesia on memory retention and the effect of this phenomenon on the number of neurons contains M1-receptors in the male Wistar rats hippocampal regions. Thirty-five male Wistar rats (200±20 g) were distributed randomly into five groups. Control group (intact samples) and 3 experimental groups with sham group (saline) were tested by the method of passive avoidance (shuttle box) in doses of 0.2, 0.5 and 1 mg/kg (intraperitoneally) as a single dose. After one week, memory test was taken from the rats. Finally, brains dissected from... Tipo: Journal article Palavras-chave: M1 receptor; Scopolamine; Avoidance memory; Hippocampus; Rat. Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400014 Registros recuperados: 3 Primeira ... 1 ... Última

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