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| Berrocal,Liliana; Fuentes,Juan A; Nicole Trombert,A; Jofré,Matías R; Villagra,Nicolás A; Valenzuela,Luis M; Mora,Guido C. |
| BACKGROUND: Salmonella enterica serovar Typhi (S. Typhi) stg operon, encoding a chaperone/usher fimbria (CU), contributes to an increased adherence to human epithelial cells. However, one report suggests that the presence of the Stg fimbria impairs the monocyte-bacteria association, as deduced by the lower level of invasion to macrophage-like cells observed when the stg fimbrial cluster was overexpressed. Nevertheless, since other CU fimbrial structures increase the entry of S. Typhi into macrophages, and considering that transcriptomic analyses revealed that stg operon is indeed expressed in macrophages, we reassessed the role of the stg operon in the interaction between S. Typhi strain STH2370 and human cells, including macrophage-like cells and... |
| Tipo: Journal article |
Palavras-chave: Salmonella Typhi; Stg; Fimbriae; Adherence; Association bacteria-eukaryotic cells. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100034 |
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