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| Justus,Barbara; Almeida,Valter Paes de; Gonçalves,Melissa Marques; Assunção,Daniele Priscila da Silva Fardin de; Borsato,Debora Maria; Arana,Andres Fernando Montenegro; Maia,Beatriz Helena Lameiro Noronha Sales; Paula,Josiane de Fátima Padilha de; Budel,Jane Manfron; Farago,Paulo Vitor. |
| ABSTRACT Lavandula dentata, popularly known as lavender, is commonly used in traditional medicine for the treatment of digestive and inflammatory disorders. The objective of this study was to analyzed the chemical oil composition, antioxidant and antimicrobial activities of the essential oil and anatomical markers of the leaf and stem of L. dentata cultivated in South Brazil. Essential oil showed an antioxidant activity similar to rutin and gallic acid when analyzed by phosphomolybdenum method. However, by the free radical DPPH and ABTS methods, it showed a slight potential antioxidant. Essential oil presented 1,8-cineol (63%) as major component, antimicrobial activity against Gram-positive, Gram-negative bacteria strains and Candida albicans, by broth... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anatomy; Antimicrobial; Antioxidant; Lamiaceae; Quality control; Volatile oil. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100441 |
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| Justus,Barbara; Arana,Andrés Fernando Montenegro; Gonçalves,Melissa Marques; Wohnrath,Karen; Boscardin,Patrícia Mathias Döll; Kanunfre,Carla Cristine; Budel,Jane Manfron; Farago,Paulo Vitor; Paula,Josiane de Fátima Padilha de. |
| Abstract Metallic nanoparticles have great potential as a chemotherapeutic agent. The aim of this study was to develop and characterize silver and gold nanoparticles using a simple method, as well as evaluating the potential cytotoxic activity in relation to the K-562 cell line. For the synthesis, a solution containing the metallic ions was subjected to magnetic stirring with the aqueous extract of Lavandula dentata L. and a change of colour was observed. With the data obtained from the analyses we concluded that the nanoparticles were successfully obtained by a simple and green method using the aqueous extract of L. dentata. The obtained nanoparticles presented a reduced size, a low level of polydispersion, and a homogenous spherical shape. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Green synthesis; Metallic nanoparticles; Myelogenous leukemia line; Cytotoxic potential; Lamiaceae. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100420 |
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| Espinoza,Joel Toribio; Novak,Robson Schimandeiro; Magalhães,Cássia Gonçalves; Budel,Jane Manfron; Justus,Barbara; Gonçalves,Melissa Marques; Boscardin,Patricia Mathias Döll; Farago,Paulo Vitor; Paula,Josiane de Fátima Padiha De. |
| The objective of this work was to develop and characterize liposomes loaded with silver nanoparticles (LAgNPs) to show improvement in stability characteristics. AgNPs were prepared by the green synthesis method with Aloe vera gel extract and exposure to sunlight. Liposomes were prepared by the modified reverse phase method. Particle size, polydispersity index, zeta potential, as well as the scanning electron microscopy (SEM) morphological aspects of AgNPs and LAgNPs were evaluated. In addition, was used flame atomic absorption spectroscopy to determine the amount of AgNP that was encapsulated in liposomes. The AgNPs presented as amorphous and polydisperse structures, with a mean diameter of 278.46 nm and zeta potential of -18.3 mV. LAgNPs had a mean... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Silver nanoparticles; Aloe vera; Sunlight; Liposomes. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100625 |
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| Gonçalves,Melissa Marques; Carneiro,Jaqueline; Justus,Barbara; Espinoza,Joel Toribio; Budel,Jane Manfron; Farago,Paulo Vitor; Paula,Josiane Padilha de. |
| Antibacterial activity and good mechanical properties are some of the characteristics required for an appropriate film dressing. A novel polymer blend was developed for wound healing application. Twenty-four formulations using the polymers chitosan, poly(vinyl alcohol) and/or ɛ-Polylysine and the plasticizer glycerol were designed using factorial design and then the films were prepared by the casting/solvent evaporation method. Seventeen films were obtained among the twenty-four proposed formulations that were characterized by Field Emission Scanning Electron Microscopy (FE-SEM) and Fourier Transform Infrared Spectroscopy (FTIR). Mechanical properties, such as tensile strength (σ), elongation at break (ɛ) and Young’s modulus (Y) as well as antibacterial... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Chitosan; Poly(vinyl alcohol); Ɛ-Polylysine; Semi-occlusive dressing. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100631 |
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