|
|
|
|
|
| FERNANDES,Kamila Rangel Primo; BITTERCOURT,Paulo Senna; SOUZA,Afonso Duarte Leão de; SOUZA,Antonia Queiroz Lima de; SILVA,Felipe Moura Araújo da; LIMA,Emerson Silva; ACHO,Leonard Domingo Rosales; NUNOMURA,Rita de Cássia Saraiva; TEIXEIRA,Ana Frazão; KOOLEN,Hector Henrique Ferreira. |
| ABSTRACT Virola venosa, popularly known in Brazil as ucuuba-da-mata, occurs naturally in the Amazon region and has potential to provide useful natural compounds, as already known for other Virola species. Therefore, the objective of this study was to determine the chemical composition of bark and leaf extracts of V. venosa, and to test the antioxidant capacity and α-glucosidase inhibition potential of their compounds. Polar extracts showed to be more active in both assays, therefore a bioactivity-guided fractionation was performed to identify the compounds that were responsible for the recorded activities. Using a combination of LC-MS/MS analysis and isolation with NMR identification, eight phenolic compounds were identified. Assays with pure compounds of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Α-glucosidase inhibition; Antioxidant compounds; Ferulic acid; Amazon. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672019000100048 |
| |
|
|
|
