Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJMBR (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Kalapothakis,E (2) Cabral,A.C. (1) Campos,LP (1) Chatzaki,M (1) Ferreira,WM (1) Moro,L (1) Pereira,NB (1) Santos,R.A.S. (1) Silva,SS (1) Vasconcelos,AC (1) Velloso,E.P. (1) Verçosa,BLA (1) Vieira,FO (1) Vieira,R. (1) Mais... Palavra-chave ACE polymorphism (I/D) (1) Angiotensin-(1-7) (1) Angiotensin-converting enzyme (1) Apoptosis (1) Cutaneous loxoscelism (1) Dermonecrosis (1) Loxosceles similis (1) Loxoscelism (1) Preeclampsia (1) Renin (1) Renin-angiotensin system (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2007 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Histopathological characterization of experimentally induced cutaneous loxoscelism in rabbits inoculated with Loxosceles similis venom J. Venom. Anim. Toxins incl. Trop. Dis. Pereira,NB; Kalapothakis,E; Vasconcelos,AC; Chatzaki,M; Campos,LP; Vieira,FO; Verçosa,BLA; Silva,SS; Ferreira,WM; Moro,L. Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus. Recent studies show that atheromatous plaque is prone to thrombosis due to endothelial cell apoptosis. To the best of our knowledge, there are no reports of microscopic dermal lesion and endothelial cell apoptosis induced by Loxosceles similis venom in the literature. Thus, the aim of the present study is to describe histological lesions induced by L. similis venom in rabbit skin and to elucidate whether apoptosis of endothelial cells is involved in the pathogenesis of loxoscelism. Forty male rabbits were split into two groups:... Tipo: Info:eu-repo/semantics/article Palavras-chave: Loxosceles similis; Loxoscelism; Dermonecrosis; Cutaneous loxoscelism; Apoptosis. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300005 Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype BJMBR Velloso,E.P.; Vieira,R.; Cabral,A.C.; Kalapothakis,E; Santos,R.A.S.. The relationship between preeclampsia and the renin-angiotensin system (RAS) is poorly understood. Angiotensin I-converting enzyme (ACE) is a key RAS component and plays an important role in blood pressure homeostasis by generating angiotensin II (Ang II) and inactivating the vasodilator angiotensin-(1-7) (Ang-(1-7)). ACE (I/D) polymorphism is characterized by the insertion (I) or deletion (D) of a 287-bp fragment, leading to changes in ACE activity. In the present study, ACE (I/D) polymorphism was correlated with plasma Ang-(1-7) levels and several RAS components in both preeclamptic (N = 20) and normotensive pregnant women (N = 20). The percentage of the ACE DD genotype (60%) in the preeclamptic group was higher than that for the control group (35%);... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin-angiotensin system; Angiotensin-converting enzyme; Renin; Angiotensin-(1-7); ACE polymorphism (I/D); Preeclampsia. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000400018 Registros recuperados: 2 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco