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| Silva,Alessandra Tesch da; Lima,Ewelyne Miranda de; Caliman,Isabela Faco; Porto,Leonardo Luiz Souza; Nascimento,Andrews Marques do; Kalil,Iêda Carneiro; Lenz,Dominik; Bissoli,Nazaré Souza; Endringer,Denise Coutinho; Andrade,Tadeu Uggere de. |
| The aims of this study were to evaluate the chemical profile, vascular reactivity, and acute hypotensive effect (AHE) of the ethanolic extract of leaves of Alpinia purpurata (Vieill) K. Schum (EEAP). Its chemical profile was evaluated using HPLC-UV, ICP-OES, and colorimetric quantification of total flavonoids and polyphenols. The vascular reactivity of the extract was determined using the mesenteric bed isolated from WKY. AHE dose-response curves were obtained for both EEAP and inorganic material isolated from AP (IAP) in WKY and SHR animals. Cytotoxic and mutagenic safety levels were determined by the micronucleus test. Rutin-like flavonoids were quantified in the EEAP (1.8 ± 0.03%), and the total flavonoid and polyphenol ratios were 4.1 ± 1.8% and 5.1 ±... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alpinia; Alpinia purpurata/phytochemistry; Alpinia purpurata/ethanolic extract/vascular reactivity; Alpinia purpurata/ethanolic extract/acute hypotensive effect; Flavonoids/quantification; Polyphenols/quantification. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200309 |
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