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Molecular investigation of a fungemia outbreak due to Candida parapsilosis in an intensive care unit BJID
Dizbay,Murat; Kalkanci,Ayse; Sezer,Busra Ergut; Aktas,Firdevs; Aydogan,Sibel; Fidan,Isil; Kustimur,Semra; Sugita,Takashi.
We investigated a nosocomial cluster of four Candida parapsilosis fungemia episodes that occurred in a neurological intensive care unit over a two-week period. The four infected patients had received parenteral nutrition through central lines, and all four had catheter-related candidemia. All of the isolates were susceptible to all of the antifungals tested, including amphotericin B, fluconazole, voriconazole, and caspofungin. They had strictly related fingerprints, based on randomly amplified polymorphic DNA analysis. Additional DNA sequencing data revealed that they were same strain. Although no isolate of Candida parapsilosis was recovered from other clinical, surveillance, or environmental samples, nosocomial spread of this yeast ceased, following the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candidemia; Candida parapsilosis; Nosocomial outbreak; Intensive care unit; RAPD; DNA sequencing.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500010
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Molecular detection of cytomegalovirus, herpes simplex virus 2, human papillomavirus 16-18 in Turkish pregnants BJID
Dinc,Bedia; Bozdayi,Gulendam; Biri,Aydan; Kalkanci,Ayse; Dogan,Bora; Bozkurt,Nuray; Rota,Seyyal.
OBJECTIVE: Human cytomegalovirus (CMV) is the most common cause of viral intrauterine infections in the world. Herpes simplex virus type 2 (HSV-2) and human papillomavirus (HPV) are the main agents of viral sexually transmitted diseases, which cause genital ulcers and genital warts, respectively. HPV infection has been linked to the majority of the anogenital malignancies. The aim of this study was to detect the existence of CMV, HSV-2 and HPV type 16-18 in Turkish pregnants by using sensitive molecular assays. METHODS: One hundred thirty-four women (18-41 years old; mean age ± SD: 27 ± 8) applied to outpatient clinic of Obstetrics and Gynecology, in between 18th - 22nd weeks of their pregnancy and a control group of 99 healthy women (15-39 years old; mean...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pregnancy; Infection; Polymerase chain reaction.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000600005
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