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	Provedor de dados BJMBR (1) Autor Chua,K.H. (1) Kee,B.P. (1) Lian,L.H. (1) Tan,S.Y. (1) Palavra-chave Interleukin-6 (1) Polymorphisms (1) Promoter (1) Systemic lupus erythematosus (1) Tipo do documento Info:eu-repo/semantics/other (1) Ano 2009 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Interleukin-6 promoter polymorphisms (-174 G/C) in Malaysian patients with systemic lupus erythematosus BJMBR Chua,K.H.; Kee,B.P.; Tan,S.Y.; Lian,L.H.. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves the inflammation of various organs upon deposition of immune complexes and is characterized by uncontrolled B cell hyperactivity. Despite intensive research on the etiology of the disease, the exact cause of the onset of SLE is unknown. The pathogenesis of the disease has been proposed to be associated with the imbalance of T helper type 1 (Th1) and Th2 cytokine activities. Elevated serum levels of interleukin-6 (IL-6), a Th2 cytokine with various functions in the regulation of human biological systems, are observed in SLE patients. In the present study, 100 Malaysian SLE patients and 100 controls were evaluated in order to determine the association of polymorphisms existing... Tipo: Info:eu-repo/semantics/other Palavras-chave: Interleukin-6; Systemic lupus erythematosus; Promoter; Polymorphisms. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000600012 Registros recuperados: 1 Primeira ... 1 ... Última

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