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Proliferation of the b -Cells of Pancreas in Diabetic Rats Treated with Urtica Dioica International Journal of Morphology
Golalipour,Mohammad Jafar; Ghafari,Soraya; Kouri,Vahid; Kestkar,Abbas Ali.
This investigation was carried out to evaluate the effect of the extract of Urtica dioica leaves on hyperglycemia and quantitative changes of b-cells in streptozotocin-diabetic rats. Forty male Wistar rats were allocated in groups of normal, diabetic, treatment and protective. Hyperglycemia induced by administrating one dose of 80 mg/kg streptozotocin (STZ) intraperitoneally. Animals in treatment group received Urtica dioica (100 mg/kg/day) for 4 weeks intraperitoneally, one week after injection of STZ. In protective group animals received U. dioica (100 mg/kg/day) for 5 days before inducing diabetes. After five weeks the animals were sacrificed and whole pancreas removed. Pancreas specimens were used for quantitative morphometric analysis after Chromealum...
Tipo: Journal article Palavras-chave: Streptozotocin; Diabetes; Urtica dioica; Rat; Pancreas; B-cells; Blood glucose.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000200011
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