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| Rueda,Andrés G.; Carreño Otero,Aurora L.; Duque,Jonny E.; Kouznetsov,Vladimir V.. |
| Abstract Aedes aegypti is the principal vector of arboviral pathogens that may cause diseases as dengue fever, chikungunya and zika. The harmful environmental effects of commercial pesticides coalesced with the development of insecticide-resistant populations encourage the discovery and generation of new alternative products as a tool to reduce the incidence of vector-borne diseases. In this work, through the classic three component Strecker reaction of commercial benzaldehydes, cyclic secondary amines and KCN, a new series of nine α-amino nitriles, girgensohnine analogs, has been synthetized and screened for larvicide and adulticide properties against A. aegypti, one of the dominant vectors of dengue, chikungunya and zika in tropical and subtropical areas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Arthropod-borne diseases; Girgensohnine analogs; Strecker reaction; Insecticidal activity; Vector control. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262018000200112 |
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