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Effect of metabolic syndrome and of its individual components on renal function of patients with type 2 diabetes mellitus BJMBR
Moehlecke,M.; Leitão,C.B.; Kramer,C.K.; Rodrigues,T.C.; Nickel,C.; Silveiro,S.P.; Gross,J.L.; Canani,L.H..
The objective of this study was to evaluate the effect of metabolic syndrome (MetS) and its individual components on the renal function of patients with type 2 diabetes mellitus (DM). A cross-sectional study was performed in 842 type 2 DM patients. A clinical and laboratory evaluation, including estimated glomerular filtration rate (eGFR) calculated by the modification of diet in renal disease formula, was performed. MetS was defined according to National Cholesterol Education Program - Adult Treatment Panel III criteria. Mean patient age was 57.9 ± 10.1 years and 313 (37.2%) patients were males. MetS was detected in 662 (78.6%) patients. A progressive reduction in eGFR was observed as the number of individual MetS components increased (one: 98.2 ± 30.8;...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Metabolic syndrome; Type 2 diabetes mellitus; Glomerular filtration rate; Modification of diet in renal disease.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700012
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Diabetic retinopathy is associated with early autonomic dysfunction assessed by exercise-related heart rate changes BJMBR
Kramer,C.K.; Leitão,C.B.; Azevedo,M.J.; Valiatti,F.B.; Rodrigues,T.C.; Canani,L.H.; Gross,J.L..
Diabetic retinopathy has been associated with cardiac autonomic dysfunction in both type 1 and type 2 diabetes mellitus (DM) patients. Heart rate (HR) changes during exercise testing indicate early alterations in autonomous tonus. The aim of the present study was to investigate the association of diabetic retinopathy with exercise-related HR changes. A cross-sectional study was performed on 72 type 2 and 40 type 1 DM patients. Autonomic dysfunction was assessed by exercise-related HR changes (Bruce protocol). The maximum HR increase, defined as the difference between the peak exercise rate and the resting rate at baseline, and HR recovery, defined as the reduction in HR from the peak exercise to the HR at 1, 2, and 4 min after the cessation of the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Type 2 diabetes mellitus; Type 1 diabetes mellitus; Heart rate changes; Diabetic retinopathy.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200011
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The prevalence of chronic diabetic complications and metabolic syndrome is not associated with maternal type 2 diabetes BJMBR
Scheffel,R.S.; Kramer,C.K.; Rados,D.V.; Pinto,L.C.; Crispim,D.; Gross,J.L.; Canani,L.H..
The maternal history of type 2 diabetes mellitus (DM) has been reported more frequently in patients with type 2 DM than paternal history. The aim of the present study was to determine if there was an association between maternal history of DM and the presence of chronic complications or metabolic syndrome (MetS) in patients with type 2 DM. A cross-sectional study was conducted with 1455 patients with type 2 DM. All outpatients with type 2 diabetes attending the endocrine clinics who fulfilled the eligibility criteria were included. Familial history of DM was determined with a questionnaire. Diabetic complications were assessed using standard procedures. The definition of MetS used was that of the World Health Organization and the National Cholesterol...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Type 2 diabetes mellitus; Metabolic syndrome; Microvascular chronic complications; Diabetic retinopathy.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200013
Registros recuperados: 3
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