Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados Ciênc. Tecnol. Aliment. (1) Autor BAYARSENGEE,Uyanga (1) CHAGNAADORJ,Amarzaya (1) CHENG,Chao-Wen (1) LEUNG,Ting-Kai (1) LIN,San-Chi (1) Palavra-chave 8-Hydroxy-2'-deoxyguanosine (1) Catalase (1) Heme oxygenase 1 (1) Nuclear factor erythroid 2-related factor 2 (1) Organosulfur compounds (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2019 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última The compound, diallyl disulfide, enriched in garlic, prevents the progression of doxorubicin-induced nephropathy Ciênc. Tecnol. Aliment. LIN,San-Chi; CHAGNAADORJ,Amarzaya; BAYARSENGEE,Uyanga; LEUNG,Ting-Kai; CHENG,Chao-Wen. Abstract The main medicinal property of garlic is mostly attributed to its organosulfur compounds, of which the oil-soluble diallyl disulfide (DADS) is the principal component of distilled garlic oil. Nuclear factor erythroid 2-related factor 2 (Nrf2) is an important cellular regulator in response to oxidative stress. This study assessed the possible protective effect of DADS on doxorubicin (Dox)-induced nephrotoxicity and its potential regulation of the Nrf2 pathway. Treatment with DADS (200 μM) induced heme oxygenase (HO)-1 and NADPH quinone oxidoreductase 1 (NQO-1) expression in a human proximal tubular cell line. The induction of HO-1 expression was suppressed in Nrf2-silenced cells. In an animal study, pretreatment with DADS relieved Dox-induced... Tipo: Info:eu-repo/semantics/article Palavras-chave: 8-Hydroxy-2'-deoxyguanosine; Catalase; Heme oxygenase 1; Nuclear factor erythroid 2-related factor 2; Organosulfur compounds. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612019000401040 Registros recuperados: 1 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco