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	Provedor de dados J. Venom. Anim. Toxins incl. Trop. Dis. (2) Autor Labio,Roger Willian de (2) Payão,Spencer Luiz Marques (2) Rasmussen,Lucas Trevizani (2) Caleman Neto,Agostinho (1) Ferraz,Mariane Avante (1) Oliveira,Juliana Garcia de (1) Orcini,Wilson Aparecido (1) Pereira,Weendelly Nayara (1) Saes,Marina (1) Smith,Marilia de Arruda Cardoso (1) Wisnieski,Fernanda (1) Zabaglia,Luanna Munhoz (1) Mais... Palavra-chave A) Gastric disease (1) Gastric cancer cagA (1) H. pylori (1) Helicobacter pylori Interleukin 8 Polymorphism -251 (T&gt (1) TNF-α Gene expression (1) Tipo do documento Info:eu-repo/semantics/article (2) Ano 2017 (1) 2015 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Interleukin 8 (-251 T>A) polymorphism in children and teenagers infected with Helicobacter pylori J. Venom. Anim. Toxins incl. Trop. Dis. Saes,Marina; Labio,Roger Willian de; Rasmussen,Lucas Trevizani; Payão,Spencer Luiz Marques. Abstract Background Helicobacter pylori (H. pylori) is a gram-negative bacterium that colonizes the human stomach and causes a variety of gastric diseases. This study evaluated the correlations between the -251 (T>A) (rs4073) polymorphism of interleukin-8 (IL-8), the etiology of gastric disease, and H. pylori infection in pediatric and adolescent patients. Methods DNA samples were obtained from 285 gastric biopsies from pediatric patients. H. pylori was detected by PCR, whereas PCR-RFLP was used to characterize the -251 (T>A) polymorphism of IL-8. Results The histological analysis revealed the presence of gastritis in 158 patients (55.44%). H. pylori was found in 71 samples (24.9%). The -251 (T>A) polymorphism revealed that 58 (29.47%)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori Interleukin 8 Polymorphism -251 (T> A) Gastric disease. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100601 Lack of association among TNF-α gene expression, -308 polymorphism (G > A) and virulence markers of Helicobacter pylori J. Venom. Anim. Toxins incl. Trop. Dis. Zabaglia,Luanna Munhoz; Ferraz,Mariane Avante; Pereira,Weendelly Nayara; Orcini,Wilson Aparecido; Labio,Roger Willian de; Caleman Neto,Agostinho; Wisnieski,Fernanda; Oliveira,Juliana Garcia de; Smith,Marilia de Arruda Cardoso; Payão,Spencer Luiz Marques; Rasmussen,Lucas Trevizani. Abstract Background Tumor necrosis factor plays a critical role in the pathogenesis of gastric diseases such as gastric cancer, and an abnormal inflammatory response has frequently been observed in dyspeptic patients. Helicobacter pylori infection can induce a gastric mucosal inflammatory response that may be influenced by -308 (G > A) polymorphisms and gene expression of theTNF-α gene. Methods One hundred and thirty-four gastric biopsy samples were collected from patients of both genders (61♂ and 73♀, mean age 40.3 ± 24.2 years) with gastric symptoms. The -308 (G > A) polymorphism of TNF-α was characterized using polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). The expression level was measured using real-time... Tipo: Info:eu-repo/semantics/article Palavras-chave: H. pylori; TNF-α Gene expression; Gastric cancer cagA. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100355 Registros recuperados: 2 Primeira ... 1 ... Última

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