|
|
| Delmas, Olivier; Holmes, Edward; Talbi, Chiraz; Dacheux, Laurent; Bouchier, Christiane; Larrous, Florence; Bourhy, Hervé. |
| Lyssaviruses are RNA viruses with single-strand, negative-sense genomes responsible for rabies-like diseases in mammals. To date, genomic and evolutionary studies have most often utilized partial genome sequences, particularly of the nucleoprotein and glycoprotein genes, with little consideration of genome-scale evolution. Herein, we report the first genomic and evolutionary analysis using complete genome sequences of all recognised lyssavirus genotypes, including 14 new complete genomes of field isolates from 6 genotypes and one genotype that is completely sequenced for the first time. In doing so we significantly increase the extent of genome sequence data available for these important viruses. Our analysis of these genome sequence data reveals that all... |
| Tipo: Text |
|
| Ano: 2008 |
URL: http://archimer.ifremer.fr/doc/00139/24994/23092.pdf |
| |
