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	Provedor de dados BJID (1) Genet. Mol. Biol. (1) Autor Lazzaretti,Rosmeri Kuhmmer (2) Sprinz,Eduardo (2) Kuhmmer,Regina (1) Linden,Rafael (1) Mattevi,Vanessa Suñé (1) Notti,Regina Kuhmmer (1) Ribeiro,Jorge Pinto (1) Tagliari,Carmela Farias da Silva (1) Vogel,Greice Meyer (1) da Silva,Patrícia Baptista (1) de Oliveira,Cáren Nunes (1) Mais... Palavra-chave Combined antiretroviral therapy (1) Dyslipidemia (1) HIV (1) HIV/AIDS (1) Lipodystrophy (1) Metabolic syndrome (1) Nutrition (1) Public Health (1) Sirtuin 1 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Dyslipidemia in HIV-infected individuals BJID Sprinz,Eduardo; Lazzaretti,Rosmeri Kuhmmer; Kuhmmer,Regina; Ribeiro,Jorge Pinto. Metabolic complications continue to play a major role in the management of HIV infection. Dyslipidemia associated with HIV infection and with the use of combined antiretroviral therapy includes elevations in triglycerides, reduced high-density cholesterol, and variable increases in low-density and total cholesterol. The association between dyslipidemia and specific antiretroviral agents has been underscored. Multiple pathogenic mechanisms by which HIV and antiretroviral agents lead to dyslipidemia have been hypothesized, but they are still controversial. The potential clinical and pathological consequences of HIV-associated hyperlipidemia are not completely known, but several studies reported an increased risk of coronary artery disease in HIV-positive... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV/AIDS; Dyslipidemia; Combined antiretroviral therapy; Nutrition; Public Health. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000600006 Investigation of SIRT1 gene variants in HIV-associated lipodystrophy and metabolic syndrome Genet. Mol. Biol. Tagliari,Carmela Farias da Silva; de Oliveira,Cáren Nunes; Vogel,Greice Meyer; da Silva,Patrícia Baptista; Linden,Rafael; Lazzaretti,Rosmeri Kuhmmer; Notti,Regina Kuhmmer; Sprinz,Eduardo; Mattevi,Vanessa Suñé. Abstract HIV-infected individuals on chronic use of highly active antiretroviral therapy (HAART) are more likely to develop adipose tissue and metabolic disorders, such as lipodystrophy (LD) and metabolic syndrome (MetS). The development of these phenotypes is known to be multifactorial. Thus, variants in genes implicated in adipogenesis and lipid metabolism may increase susceptibility to LD and MetS. Sirtuin 1 (SIRT1) may influence the outcome of these disturbances due to its role in the regulation of transcription factors involved in energy regulation. Therefore, we genotyped four polymorphisms located in SIRT1 (rs2273773 T>C, rs12413112 G>A, rs7895833 A>G, rs12049646 T>C) in 832 HIV-infected patients receiving HAART by real-time polymerase... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; Lipodystrophy; Metabolic syndrome; Sirtuin 1. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000100105 Registros recuperados: 2 Primeira ... 1 ... Última

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