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	Provedor de dados Anais da ABC (AABC) (1) Autor Jian,Jhin-Hao (1) Leu,Jyh-Gang (1) Liang,Yao-Jen (1) Lin,Chin-Yao (1) Shih,Chin-Yu (1) Palavra-chave Alpha lipoic acid (1) Anti-oxidant (1) Diabetic nephropathy (1) Epigallocatechin gallate (1) Receptor of advanced glycation end products (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2013 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Epigallocatechin-3-gallate combined with alpha lipoic acid attenuates high glucose-induced receptor for advanced glycation end products (RAGE) expression in human embryonic kidney cells Anais da ABC (AABC) Leu,Jyh-Gang; Lin,Chin-Yao; Jian,Jhin-Hao; Shih,Chin-Yu; Liang,Yao-Jen. The anti-oxidant effects of epigallocatechin gallate (EGCG) and alpha lipoic acid (ALA) have been demonstrated in previous studies. The kidney protection effects of EGCG and ALA in patients with kidney injury are still under investigation. The purpose of this study is to investigate the anti-inflammatory and anti-oxidant effects of EGCG and ALA on high glucose-induced human kidney cell damage. EGCG inhibited high glucose(HG)-induced TNF-α and IL-6 production in human embryonic kidney (HEK) cells. Both EGCG and ALA decreased HG-induced receptor of advanced glycation end products (RAGE) mRNA and protein expressions in HEK cells. EGCG and ALA also recovered HG-inhibited superoxide dismutase production and decreased ROS expressions in HEK cells. The synergism... Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetic nephropathy; Receptor of advanced glycation end products; Epigallocatechin gallate; Alpha lipoic acid; Anti-oxidant. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000200745 Registros recuperados: 1 Primeira ... 1 ... Última

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