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Active anti-acetylcholinesterase component of secondary metabolites produced by the endophytic fungi of Huperzia serrata Electron. J. Biotechnol.
Wang,Zhejian; Ma,Zhao; Wang,Lili; Tang,Chengchen; Hu,Zhibi; Chou,GuiXin; Li,Wankui.
Background An endophytic fungus lives within a healthy plant during certain stages of, or throughout, its life cycle. Endophytic fungi do not always cause plant disease, and they include fungi that yield different effects, including mutual benefit, and neutral and pathogenic effects. Endophytic fungi promote plant growth, improve the host plant's resistance to biotic and abiotic stresses, and can produce the same or similar biologically active substances as the host. Thus, endophytic fungal products have important implications in drug development. Result Among the numerous endophytic fungi, we identified two strains, L10Q37 and LQ2F02, that have anti-acetylcholinesterase activity, but the active compound was not huperzine A. The aim of this study was to...
Tipo: Journal article Palavras-chave: Anti-acetylcholinesterase activity; Acetylcholinesterase inhibitor; Biological characteristics; Endophytic fungi.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000600003
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