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Long-term, regular remote ischemic preconditioning improves endothelial function in patients with coronary heart disease BJMBR
Liang,Y.; Li,Y.P.; He,F.; Liu,X.Q.; Zhang,J.Y..
Remote ischemic preconditioning (RIPre) can prevent myocardial injury. The purpose of this study was to assess the beneficial effects of long-term regular RIPre on human arteries. Forty patients scheduled for coronary artery bypass graft (CABG) surgery were assigned randomly to a RIPre group (n=20) or coronary heart disease (CHD) group (n=20). Twenty patients scheduled for mastectomy were enrolled as a control group. RIPre was achieved by occluding arterial blood flow 5 min with a mercury sphygmomanometer followed by a 5-min reperfusion period, and this was repeated 4 times. The RIPre procedure was repeated 3 times a day for 20 days. In all patients, arterial fragments discarded during surgery were collected to evaluate endothelial function by...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Remote ischemic preconditioning; Endothelial function; Coronary heart disease; STAT-3.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000600568
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