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Urinary semaphorin 3A as an early biomarker to predict contrast-induced acute kidney injury in patients undergoing percutaneous coronary intervention BJMBR
Ning,Li; Li,Zhiguo; Wei,Dianjun; Chen,Haiyan; Yang,Chao; Wu,Dawei; Wang,Yanchun; Zhang,Jingwei.
Contrast-induced acute kidney injury (CI-AKI) is a serious complication of diagnostic coronary angiograph and percutaneous coronary intervention (PCI). However, the exact pathophysiological mechanisms underlying CI-AKI development are largely unknown. The present study examined whether urinary semaphorin 3A levels predict the development of CI-AKI in patients undergoing PCI. This study enrolled 168 patients with stable angina undergoing elective PCI. Serial urine samples, obtained at baseline and 2, 6, 12, 24, 36, and 48 h post-PCI were analyzed by semaphorin 3A and neutrophil gelatinase-associated lipocalin (NGAL) ELISA kit. AKI was defined as an increase in serum creatinine beyond 50% according to the RIFLE classification system. Receiver operator...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Contrast-induced acute kidney injury; Percutaneous coronary intervention; Semaphorin 3A; Neutrophil gelatinase-associated lipocalin; Biomarker.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000400618
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Identification of genes related to high royal jelly production in the honey bee (Apis mellifera) using microarray analysis Genet. Mol. Biol.
Nie,Hongyi; Liu,Xiaoyan; Pan,Jiao; Li,Wenfeng; Li,Zhiguo; Zhang,Shaowu; Chen,Shenglu; Miao,Xiaoqing; Zheng,Nenggan; Su,Songkun.
Abstract China is the largest royal jelly producer and exporter in the world, and high royal jelly-yielding strains have been bred in the country for approximately three decades. However, information on the molecular mechanism underlying high royal jelly production is scarce. Here, a cDNA microarray was used to screen and identify differentially expressed genes (DEGs) to obtain an overview on the changes in gene expression levels between high and low royal jelly producing bees. We developed a honey bee gene chip that covered 11,689 genes, and this chip was hybridised with cDNA generated from RNA isolated from heads of nursing bees. A total of 369 DEGs were identified between high and low royal jelly producing bees. Amongst these DEGs, 201 (54.47%) genes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Honeybee; Royal jelly production; Gene chip; Molecular marker; Differentially expressed genes.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000500781
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