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	Provedor de dados BJMBR (3) Autor Liang,Y. (3) Cao,C. (1) He,F. (1) Jiang,L. (1) Li,Y.P. (1) Liu,S. (1) Liu,X.Q. (1) Tang,Y. (1) Wang,Q. (1) Yang,N. (1) Yang,P. (1) Yang,T. (1) Yin,Q. (1) Zhang,J.Y. (1) Zhao,J. (1) Mais... Palavra-chave Cell apoptosis (1) Cell viability (1) Coronary heart disease (1) Endothelial function (1) Lung cancer (1) Marker (1) MicroRNA-486 (1) Pancreatic ductal adenocarcinoma (1) Propofol (1) Remote ischemic preconditioning (1) STAT-3 (1) TGF-β1 (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2017 (1) 2016 (1) 2015 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Clinical and prognostic significance of serum transforming growth factor-beta1 levels in patients with pancreatic ductal adenocarcinoma BJMBR Zhao,J.; Liang,Y.; Yin,Q.; Liu,S.; Wang,Q.; Tang,Y.; Cao,C.. Pancreatic ductal adenocarcinoma (PDAC) has a poor 5-year survival rate of 5%. Biomarkers for the early detection of pancreatic cancer are urgently needed. Transforming growth factor-beta1 (TGF-β1) is elevated in the tissues and plasma of patients with PDAC. However, no studies systemically report prognostic significance of plasma TGF-β1 levels in PDAC. In the present study, we assessed the prognostic significance of serum TGF-β levels in patients with PDAC. TGF-β levels were determined in serum from 146 PDAC patients, and 58 patients with benign pancreatic conditions. Regression models were used to correlate TGF-β levels to gender, age, stage, class, and metastasis. Survival analyses were performed using multivariate Cox models. Serum levels of TGF-β1... Tipo: Info:eu-repo/semantics/article Palavras-chave: Pancreatic ductal adenocarcinoma; Marker; TGF-β1. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000800705 Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression BJMBR Yang,N.; Liang,Y.; Yang,P.; Yang,T.; Jiang,L.. Propofol is a frequently used intravenous anesthetic agent. Recent studies show that propofol exerts a number of non-anesthetic effects. The present study aimed to investigate the effects of propofol on lung cancer cell lines H1299 and H1792 and functional role of microRNA (miR)-486 in these effects. H1299 and/or H1792 cells were treated with or without propofol and transfected or not with miR-486 inhibitor, and then cell viability and apoptosis were analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and flow cytometry. The expression of miR-486 was determined by quantitative real-time polymerase chain reaction (qRT-PCR) with or without propofol treatment. Western blot was performed to analyze the protein expression of Forkhead... Tipo: Info:eu-repo/semantics/article Palavras-chave: Propofol; Lung cancer; Cell viability; Cell apoptosis; MicroRNA-486. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000100601 Long-term, regular remote ischemic preconditioning improves endothelial function in patients with coronary heart disease BJMBR Liang,Y.; Li,Y.P.; He,F.; Liu,X.Q.; Zhang,J.Y.. Remote ischemic preconditioning (RIPre) can prevent myocardial injury. The purpose of this study was to assess the beneficial effects of long-term regular RIPre on human arteries. Forty patients scheduled for coronary artery bypass graft (CABG) surgery were assigned randomly to a RIPre group (n=20) or coronary heart disease (CHD) group (n=20). Twenty patients scheduled for mastectomy were enrolled as a control group. RIPre was achieved by occluding arterial blood flow 5 min with a mercury sphygmomanometer followed by a 5-min reperfusion period, and this was repeated 4 times. The RIPre procedure was repeated 3 times a day for 20 days. In all patients, arterial fragments discarded during surgery were collected to evaluate endothelial function by... Tipo: Info:eu-repo/semantics/article Palavras-chave: Remote ischemic preconditioning; Endothelial function; Coronary heart disease; STAT-3. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000600568 Registros recuperados: 3 Primeira ... 1 ... Última

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