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Serum and cerebrospinal fluid S100B concentrations in patients with neurocysticercosis BJMBR
Lima,J.E.; Walz,R.; Tort,A.; Souza,D.; Portela,L.; Bianchin,M.M.; Takayanagui,O.M.; Leite,J.P..
The clinical manifestations of neurocysticercosis (NC) are varied and depend on the number and location of cysts, as well as on the host immune response. Symptoms usually occur in NC when cysticerci enter a degenerative course associated with an inflammatory response. The expression of brain damage markers may be expected to increase during this phase. S100B is a calcium-binding protein produced and released predominantly by astrocytes that has been used as a marker of reactive gliosis and astrocytic death in many pathological conditions. The aim of the present study was to investigate the levels of S100B in patients in different phases of NC evolution. Cerebrospinal fluid and serum S100B concentrations were measured in 25 patients with NC: 14 patients...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neurocysticercosis; S100B; Cerebrospinal fluid; Umin quotient; Glial marker.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100015
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Use of neuron-specific enolase for assessing the severity and outcome of neurological disorders in patients BJMBR
Lima,J.E.; Takayanagui,O.M.; Garcia,L.V.; Leite,J.P..
Neuron-specific enolase (NSE) is a glycolytic enzyme present almost exclusively in neurons and neuroendocrine cells. NSE levels in cerebrospinal fluid (CSF) are assumed to be useful to estimate neuronal injury and clinical outcome of patients with serious clinical manifestations such as those observed in stroke, head injury, anoxic encephalopathy, encephalitis, brain metastasis, and status epilepticus. We compared levels of NSE in serum (sNSE) and in CSF (cNSE) among four groups: patients with meningitis (N = 11), patients with encephalic injuries associated with impairment of consciousness (ENC, N = 7), patients with neurocysticercosis (N = 25), and normal subjects (N = 8). Albumin was determined in serum and CSF samples, and the albumin quotient was used...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Neuronal damage; Neuron-specific enolase; Cerebrospinal fluid; Albumin quotient.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100003
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