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Theories about evolutionary origins of human hepatitis B virus in primates and humans BJID
Souza,Breno Frederico de Carvalho Dominguez; Drexler,Jan Felix; Lima,Renato Santos de; Rosário,Mila de Oliveira Hughes Veiga do; Netto,Eduardo Martins.
Introduction:The human hepatitis B virus causes acute and chronic hepatitis and is considered one of the most serious human health issues by the World Health Organization, causing thousands of deaths per year. There are similar viruses belonging to the Hepadnaviridae family that infect non-human primates and other mammals as well as some birds. The majority of non-human primate virus isolates were phylogenetically close to the human hepatitis B virus, but like the human genotypes, the origins of these viruses remain controversial. However, there is a possibility that human hepatitis B virus originated in primates. Knowing whether these viruses might be common to humans and primates is crucial in order to reduce the risk to humans.Objective:To review the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis B virus; Hepadnaviridae; Non-human primates; Evolutionary origins.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500535
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