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	Provedor de dados BJMBR (1) Autor Campos,A.H. (1) Lima,V.C. (1) Rosa,W.C.M. (1) Palavra-chave Coronary artery angioplasty (1) Coronary restenosis (1) Immunosuppression (1) Inflammation mediators (1) Oral sirolimus (1) Percutaneous coronary intervention (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Effect of oral sirolimus therapy on inflammatory biomarkers following coronary stenting BJMBR Rosa,W.C.M.; Campos,A.H.; Lima,V.C.. We studied the effect of oral sirolimus, administered to prevent and treat in-stent restenosis (ISR), on the variation of serum levels of inflammatory markers following coronary stenting with bare metal stents. The mean age of the patients was 56 ± 13 years, 65% were males and all had clinically manifested ischemia. Serum levels of high sensitivity C-reactive protein (hs-CRP) concentration were determined by chemiluminescence and serum levels of all other biomarkers by ELISA. One group of patients at high risk for ISR received a loading oral dose of 15 mg sirolimus and 5 mg daily thereafter for 28 days after stenting (SIR-G). A control group (CONT-G) was submitted to stenting without sirolimus therapy. The increase in hs-CRP concentration was highest at 24... Tipo: Info:eu-repo/semantics/article Palavras-chave: Inflammation mediators; Oral sirolimus; Percutaneous coronary intervention; Coronary artery angioplasty; Coronary restenosis; Immunosuppression. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000800012 Registros recuperados: 1 Primeira ... 1 ... Última

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