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Shu,H.F.; Gao,F.Y.; Zhang,C.Q.; Liu,S.Y.; Zhang,Z.Y.; Song,Y.C.; Qiu,K.J.; Yang,H.. |
The molecular mechanisms and potential clinical applications of neural precursor cells have recently been the subject of intensive study. Dlx5, a homeobox transcription factor related to the distal-less gene in Drosophila, was shown to play an important role during forebrain development. The subventricular zone (SVZ) in the adult brain harbors the largest abundance of neural precursors. The anterior SVZ (SVZa) contains the most representative neural precursors in the SVZ. Further research is necessary to elucidate how Dlx5-related genes regulate the differentiation of SVZa neural precursors. Here, we employed immunohistochemistry and molecular biology techniques to study the expression of Dlx5 and related homeobox genes Er81 and Islet1 in neonatal rat... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neural precursors; Dlx5; Green fluorescent protein; Recombinant plasmids. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000200008 |
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