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| Zhu,Xiang-Yu; Liu,Ning; Liu,Wei; Song,Shao-Wei; Guo,Ke-Jian. |
| Integrin-linked kinase (ILK) is an ankyrin repeat-containing serine-threonine protein kinase that is involved in the regulation of integrin-mediated processes such as cancer cell proliferation, migration and invasion. In this study, we examined the effect of a lentivirus-mediated knockdown of ILK on the proliferation, migration and invasion of pancreatic cancer (Panc-1) cells. Immunohistochemical staining showed that ILK expression was enhanced in pancreatic cancer tissue. The silencing of ILK in human Panc-1 cells led to cell cycle arrest in the G0/G1 phase and delayed cell proliferation, in addition to down-regulating cell migration and invasion. The latter effects were mediated by up-regulating the expression of E-cadherin, a key protein in cell... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: E-cadherin; Epithelial-mesenchymal transition (EMT); Integrin-linked kinase (ILK); Panc-1 cell line; RNA interference (RNAi). |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300022 |
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| Zhu,Guoping; Xu,Liuxiong; Dai,Xiaojie; Liu,Wei. |
| Age and growth parameters were estimated for the yellowfin tuna Thunnus albacares (Bonnaterre, 1788). Atotal of 443 individuals were sampled from China longline fisheries in the eastern and central Pacific Ocean from February to November 2006. The von Bertalanffy growth parameters were estimated at L∞ = 175.9 cm fork length, k = 0.52 year-1, and t0 = 0.19 year. The total mortality rate (Z) was estimated to be from 1.19 to 1.93 year-1, the fishing mortality (F) and the natural mortality (M) were calculated to be 0.91 year-1 and 0.65 year-1, respectively. The rate of exploitation (U) was estimated to be 0.46. This study provides estimates of growth and mortality rate for yellowfin tuna in the eastern and central Pacific Ocean, which may be used as biological... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biological parameters; Size frequency analysis; Yellowfin tuna. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702011000200007 |
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| Jaganathan,Ganesh K.; Song,Danping; Liu,Wei; Han,Yingying; Liu,Baolin. |
| ABSTRACT Seeds of Nelumbo nucifera do not imbibe water, and thus have physical dormancy (PY). However, a proportion of seeds are permeable to water, and so we hypothesized that variation in moisture content is a reason for the development of both permeable and impermeable seeds. The permeable proportion of seeds present in a lot collected from Suzhou, China, was separated using an imbibition test. The permeable proportion had an average moisture content of 15.6 %, compared with 8.5 % for impermeable seeds. Drying permeable seeds above silica gel to 10 % and 8 % f. wb., resulted in 77 and 100 % impermeable seeds, respectively, compared with no impermeable seeds at 15 % moisture content. Dried to 10 % moisture content, and incubated above water in an... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dormancy reversal; Maternal environment; Maturation drying; Moisture content; Physical dormancy. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-33062017000400639 |
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| Mu,Xia; Xu,Yan; Yang,Tingxiu; Zhang,Ji; Wang,Chong; Liu,Wei; Chen,Jing; Tang,Luyu; Yang,Huai. |
| Abstract Objective Hand hygiene (HH) is a critical component for controlling hospital-acquired infection (HAI). The present study was designed to develop an intervention approach to improve compliance with HH among healthcare workers in a hospital setting. Methods The HH intervention study was conducted in Guizhou Provincial People's Hospital, Guiyang, China and organized by its Department of HAI Management. It was an observational, prospective, quasiexperimental (before-after intervention) study. The study was divided into two phases: the baseline phase and the intervention phase. The investigative team included clinical monitoring staff and infection control practitioners who received a series of instructions on HH compliance, monitoring skills, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hand hygiene; Compliance; Hospital-acquired infection. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702016000500413 |
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| Cheng,Fangjun; Li,Zhangcheng; Lan,Shimei; Liu,Wei; Li,Xiaoyan; Zhou,Zuoyong; Song,Zhenhui; Wu,Juan; Zhang,Manli; Shan,Wenjie. |
| Abstract Klebsiella pneumoniae is important human and animal pathogen that causes a wide spectrum of infections. In this study, isolates from cattle nasal swabs samples were identified by 16S rRNA, and to evaluate the antimicrobial susceptibility, virulence gene carrying levels, and multilocus sequence typing of K. pneumoniae isolates. 33 isolates of K. pneumoniae were isolated and identified in 213 nasal swabs samples, of which 12 were hypervirulent K. pneumoniae strains. Extended Spectrum Beta-Lactamases genes were found in 93.4% of the strains. Of which, TEM was the most prevalent (93.4%), followed by CTX-M and SHV were 57.6% and 39.4%, respectively. A main mutation pattern of quinoloneresistance-determining region, Thr83-Ieu and Asp87-Asn in gyrA and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cattle; Antimicrobial susceptibility; Klebsiella pneumonia; MLST; Virulence genes. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822018000500093 |
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