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	Provedor de dados BJPS (2) Autor Almeida,Hugo (2) Amaral,Maria Helena (2) Lobão,Paulo (2) Palavra-chave Antibiotics (1) Bacteria (1) Biotechnology (1) Cetyl alcohol (1) Excipients (1) Hybridoma technique (1) Hydrogenated castor oil (1) Ibuprofen/lipid microparticles (1) Ibuprofen/release profile (1) Ibuprofen/solid dispersions (1) Recombinant DNA (1) Stearic acid (1) Vaccines (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2012 (1) 2011 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Comparative study of sustained-release lipid microparticles and solid dispersions containing ibuprofen BJPS Almeida,Hugo; Amaral,Maria Helena; Lobão,Paulo. Ibuprofen is one of the most important non-steroidal anti-inflammatory drugs used in the treatment of inflammatory diseases. In its pure state, ibuprofen presents poor physical and mechanical characteristics and its use in solid dosage forms needs the addition of excipients that improve these properties. The selection of the best excipients and the most suitable pharmaceutical dosage form to carry ibuprofen is very important for the industrial success of this drug. Given these factors, lipid microparticles and solid dispersions of ibuprofen with cetyl alcohol, stearic acid, and hydrogenated castor oil were prepared. These formulations were intended to improve the physical and mechanical characteristics and to sustain the release of this drug. Physical... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ibuprofen/solid dispersions; Ibuprofen/release profile; Ibuprofen/lipid microparticles; Ibuprofen/release profile; Excipients; Cetyl alcohol; Stearic acid; Hydrogenated castor oil. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300020 Drugs obtained by biotechnology processing BJPS Almeida,Hugo; Amaral,Maria Helena; Lobão,Paulo. In recent years, the number of drugs of biotechnological origin available for many different diseases has increased exponentially, including different types of cancer, diabetes mellitus, infectious diseases (e.g. AIDS Virus / HIV) as well as cardiovascular, neurological, respiratory, and autoimmune diseases, among others. The pharmaceutical industry has used different technologies to obtain new and promising active ingredients, as exemplified by the fermentation technique, recombinant DNA technique and the hybridoma technique. The expiry of the patents of the first drugs of biotechnological origin and the consequent emergence of biosimilar products, have posed various questions to health authorities worldwide regarding the definition, framework, and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Biotechnology; Recombinant DNA; Hybridoma technique; Bacteria; Antibiotics; Vaccines. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200002 Registros recuperados: 2 Primeira ... 1 ... Última

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