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| CRUZ,WANISE M. SOUZA; GUIMARÃES,SHEILA M.S.; MACIEL,GABRIELLE C.; HUGUENIN,ANA BEATRIZ A.; CARVALHO,MONICQUE E.M. DE; COSTA,BÁRBARA O.; SILVA,GEISIANE A. DA; COLAFRANCESCHI,ALEXANDRE S.; SCALCO,FERNANDA B.; RIBEIRO,MARCIA. |
| Abstract Coronary artery bypass grafting reduces plasma L-carnitine and may impair the production of myocardial energy. L-carnitine supplementation may elevate plasma L-carnitine and increase cardiac mechanical efficiency. The objective of this study was to verify the recovery of preoperative plasma LC in patients with heart failure undergoing coronary artery bypass grafting supplemented with a daily oral dose of 50 mg / kg. Volunteers with ischemic heart failure who underwent surgery were randomized into a supplemented group (A-received 50 mg / kg L-carnitine) or placebo group (B) for 60 days. Supplementation was started on the third postoperative day. The spectrophotometric enzymatic method was used to quantify plasma L-carnitine. In the preoperative... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ischemic heart failure; Myocardial revascularization surgery; Oral L-carnitine supplementation; Plasma L-carnitine. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000603099 |
