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BARROS,BÁRBARA R.S.; BARBOZA,BRUNO RAFAEL; RAMOS,BÁRBARA A.; MOURA,MAIARA C. DE; COELHO,LUANA C.B.B.; NAPOLEÃO,THIAGO HENRIQUE; CORREIA,MARIA TEREZA S.; PAIVA,PATRÍCIA MARIA G.; CRUZ FILHO,IRANILDO JOSÉ DA; SILVA,TÚLIO DIEGO DA; LIMA,CLÁUDIA S.A.; MELO,CRISTIANE M.L. DE. |
Abstract: Currently, the research of new natural compounds with biological potential demonstrates great ethnopharmacological importance. In this study, we evaluated the biological properties promoted by saline extract from Malpighia emarginata DC leaves, whose objective is to evaluate the antioxidant, antimicrobial and cytotoxicity potential. Phytochemical characterization was performed by UPLC-MS chromatography to identify the chemical compounds. For the antioxidant potential, DPPH, ATT and FRAP methods were used. The antibacterial and antifungal tests were performed evaluating the MIC50, MIC90, CMB and CMF parameters. Moreover, antibiofilm action was evaluated. Cytotoxicity and proliferation were performed using splenocytes from Balb/c mice and were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bioactive compounds; Cytotoxicity; Malpighia emarginata DC; Phytochemical. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000100627 |
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