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Spatial cognition and memory: a reversible lesion with lidocaine into the anteromedial/posterior parietal cortex (AM/PPC) affects differently working and long-term memory on two foraging tasks 48
ESPINA-MARCHANT,PABLO; PINTO-HAMUY,TERESA; BUSTAMANTE,DIEGO; MORALES,PAOLA; ROBLES,LUIS; HERRERA-MARSCHITZ,MARIO.
Place memory is relevant for exploration and forage behaviour. When food supply is dispersed, a win-shift has advantage over a win-stay strategy. In the Olton Octagonal Maze, the rat follows a win-shift strategy using working memory. However, in the Olton 4x4 version, the rat follows a win-stay strategy, using both working and long-term memories. It has been suggested that the neocortex is required for the resolution of tasks demanding long-term, but not for that demanding working memory alone. The role of anteromedial/posterior parietal cortex (AM/PPC) was investigated here, using a reversible lesion induced by intracerebral lidocaine infusion. Long-Evans rats were implanted with guide cannulae into the AM/PPC and trained in an Olton 4x4 maze, counting...
Tipo: Journal article Palavras-chave: Anteromedial/posterior parietal cortex hippocampus lidocaine; Long-term memory working memory intracerebral infusion rat.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000500003
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Long lasting structural changes in primary motor cortex after motor skill learning: a behavioural and stereological study 48
MORALES,PAOLA.
Many motor skills, once acquired, are stored over a long time period, probably sustained by permanent neuronal changes. Thus, in this paper we have investigated with quantitative stereology the generation and persistence of neuronal density changes in primary motor cortex (MI) following motor skill learning (skilled reaching task). Rats were trained a lateralised reaching task during an "early" (22-31 days oíd) or "late" (362-371 days oíd) postnatal period. The trained and corresponding control rats were sacrificed at day 372, immediately after the behavioural testing. The "early" trained group preserved the learned skilled reaching task when tested at day 372, without requiring any additional training. The "late" trained group showed a similar capacity to...
Tipo: Journal article Palavras-chave: Motor cortex; Plasticity; Persistence of structural changes; Aging; Motor skill learning (skilled reaching task); Stereology; Rat.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000400005
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