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	Provedor de dados BJMBR (1) Autor Andrade,Z.A. (1) Lemos,Q.T. (1) Magalhães-Santos,I.F. (1) Palavra-chave Capillaria hepatica model (1) Hepatic fibrosis (1) Immunological tolerance (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2003 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Immunological basis of septal fibrosis of the liver in Capillaria hepatica-infected rats BJMBR Lemos,Q.T.; Magalhães-Santos,I.F.; Andrade,Z.A.. Rats infected with the helminth Capillaria hepatica regularly develop septal fibrosis of the liver similar to that induced by repeated ip injections of pig serum. Fibrosis starts when the focal parasitic lesions begin to show signs of resorption, thus suggesting an immunologically mediated pathogenesis of this fibrosis. To explore this possibility, the development of C. hepatica-related hepatic fibrosis was observed in rats exposed to worm antigens from the first neonatal day onward. Wistar rats (150 g) were either injected ip with an extract of C. hepatica eggs (protein concentration: 1 mg/ml) or received immature eggs by gavage from the first neonatal day until adult life and were then infected with 500 embryonated eggs. Changes were monitored on the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Capillaria hepatica model; Hepatic fibrosis; Immunological tolerance. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900009 Registros recuperados: 1 Primeira ... 1 ... Última

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