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	Provedor de dados Nature Precedings (3) Autor Mahendra P. Darokar (3) Suaib Luqman (3) Suchita Srivastava (3) Suman P. S. Khanuja (3) Sudeep Tandon (2) Alok Somvanshi (1) Arvind S. Negi (1) Atiya Fatima (1) Chandan S. Chanotiya (1) J K. Kumar (1) Karuna Shanker (1) Ritesh Kumar (1) Shubhangi Kaushik (1) Mais... Palavra-chave Molecular Cell Biology (3) Pharmacology (3) Biotechnology (2) Microbiology (2) Chemistry (1) Tipo do documento Poster (3) Ano 2012 (3) País United Kingdom (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Biotransformation of artemisinin mediated through fungal strains for obtaining derivatives with novel activities Nature Precedings Suchita Srivastava; Suaib Luqman; Atiya Fatima; Mahendra P. Darokar; Arvind S. Negi; J K. Kumar; Karuna Shanker; Chandan S. Chanotiya; Sudeep Tandon; Suman P. S. Khanuja. Artemisinin, a sesquiterpene lactone, is the active antimalarial constituent of Artemisia annua. Several fungal strains Saccharomyces cerevisiae, Aspergillus flavus, Aspergillus niger and Picchia pastoris were used to biotransform artemisinin. Among these strains, A. flavus was the only microorganism capable of transforming artemisinin to deoxyartemisinin in higher yields than the previous reports. The structure of deoxyartemisinin was elucidated by spectroscopy. Deoxyartemisinin showed antibacterial activity against Staphylococcus aureus, S. epidermidis and S. mutans at a minimum inhibitory concentration (MIC) of 1 mg/mL compared to artemisinin whose MIC was >2 mg/mL. Tipo: Poster Palavras-chave: Biotechnology; Chemistry; Microbiology; Molecular Cell Biology; Pharmacology. Ano: 2012 URL: http://precedings.nature.com/documents/6925/version/1 Bioconversion of eugenol into food flavouring agent vanillin Nature Precedings Suaib Luqman; Sudeep Tandon; Alok Somvanshi; Suchita Srivastava; Mahendra P. Darokar; Suman P. S. Khanuja. Microorganisms have the ability to chemically modify a wide variety of organic compounds by a process referred to as biological or microbial transformation, or in general, bioconversion. The microbial cells and their catalytic machinery (enzymes) accept a wide array of complex molecules as substrates, yielding products with unparallel chiral (enantio-), positional (region-) and chemical (chemo-) selectivity through various biochemical reactions. The present study was formulated on the objective of the conversion of abundantly available phytomolecules eugenol into vanillin, a compound of industrial importance, using microorganisms Aspergillus flavus, Aspergillus niger and Pseudomonas aeruginosa. These microbes were found to be capable of converting eugenol... Tipo: Poster Palavras-chave: Biotechnology; Microbiology; Molecular Cell Biology; Pharmacology. Ano: 2012 URL: http://precedings.nature.com/documents/6926/version/1 Concentration-dependent free radical scavenging and ferric reducing ability of Vetiveria zizanioides (L.) Nash: Protective effect of vetiver root extract during oxidative stress Nature Precedings Suaib Luqman; Ritesh Kumar; Shubhangi Kaushik; Suchita Srivastava; Mahendra P. Darokar; Suman P. S. Khanuja. Vetiveria zizanioides, popularly known as ‘KHUS’ grass, has been known to India since ancient times. It is the major source of well-known oil of vetiver, which is used in medicine and in perfumery. A concentration-dependent ferric reducing, free radical scavenging and antioxidant activity of two genotypes, namely KS 1 and gulabi of vetiver (Vetiveria zizanioides L. Nash) root, were evaluated by using in vitro assays: the ferric reducing antioxidant power (FRAP), 1, 1-Diphenyl-2-picrylhydrazyl (DPPH), total phenolic content (TPC), total antioxidant capacity (TAC) and reducing power (RP) assay. A positive co-relation was observed between FRAP, DPPH and TPC of cv KS 1, whereas TAC and RP showed a negative co-relation. A significant... Tipo: Poster Palavras-chave: Molecular Cell Biology; Pharmacology. Ano: 2012 URL: http://precedings.nature.com/documents/6920/version/1 Registros recuperados: 3 Primeira ... 1 ... Última

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