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	Provedor de dados BJMBR (3) Autor Fernandez,R. (3) Malnic,G. (3) Carraro-Lacroix,L.R. (1) Fabris,R. (1) Fernandes,L.C. (1) Lessa,L.M.A. (1) Piechnik,J. (1) Tararthuch,A.L. (1) Mais... Palavra-chave H+-ATPase (2) ATP (1) CAMP (1) Cachexia (1) Cell pH (1) Chloride channels (1) Cl- (1) Cl-/H+ Antiporter (1) Fish oil supplementation (1) Glomerular filtration rate (1) Intracellular organelles (1) Plasma membranes (1) Renal function (1) Sodium excretion (1) Valinomycin (1) Walker 256 tumor (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2009 (1) 2007 (1) 2004 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Cl- and regulation of pH by MDCK-C11 cells BJMBR Tararthuch,A.L.; Fernandez,R.; Malnic,G.. The interaction between H+ extrusion via H+-ATPase and Cl- conductance was studied in the C11 clone of MDCK cells, akin to the intercalated cells of the collecting duct. Cell pH (pHi) was measured by fluorescence microscopy using the fluorescein-derived probe BCECF-AM. Control recovery rate measured after a 20 mM NH4Cl acid pulse was 0.136 ± 0.008 pH units/min (dpHi/dt) in Na+ Ringer and 0.032 ± 0.003 in the absence of Na+ (0 Na+). With 0 Na+ plus the Cl- channel inhibitor NPPB (10 µM), recovery was reduced to 0.014 ± 0.001 dpHi/dt. 8-Br-cAMP, known to activate CFTR Cl- channels, increased dpHi/dt in 0 Na+ to 0.061 ± 0.009 and also in the presence of 46 nM concanamycin and 50 µM Schering 28080. Since it is thought that the Cl- dependence of H+-ATPase might... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cell pH; CAMP; ATP; H+-ATPase; Valinomycin; Cl-. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000500012 Physiological implications of the regulation of vacuolar H+-ATPase by chloride ions BJMBR Carraro-Lacroix,L.R.; Lessa,L.M.A.; Fernandez,R.; Malnic,G.. Vacuolar H+-ATPase is a large multi-subunit protein that mediates ATP-driven vectorial H+ transport across the membranes. It is widely distributed and present in virtually all eukaryotic cells in intracellular membranes or in the plasma membrane of specialized cells. In subcellular organelles, ATPase is responsible for the acidification of the vesicular interior, which requires an intraorganellar acidic pH to maintain optimal enzyme activity. Control of vacuolar H+-ATPase depends on the potential difference across the membrane in which the proton ATPase is inserted. Since the transport performed by H+-ATPase is electrogenic, translocation of H+-ions across the membranes by the pump creates a lumen-positive voltage in the absence of a neutralizing current,... Tipo: Info:eu-repo/semantics/article Palavras-chave: H+-ATPase; Chloride channels; Cl-/H+ Antiporter; Intracellular organelles; Plasma membranes. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000200002 Effect of chronic fish oil supplementation on renal function of normal and cachectic rats BJMBR Fernandez,R.; Piechnik,J.; Fabris,R.; Malnic,G.; Fernandes,L.C.. In the present study we determined the effect of chronic diet supplementation with n-3 PUFA on renal function of healthy and cachectic subjects by providing fish oil (1 g/kg body weight) to female rats throughout pregnancy and lactation and then to their offspring post-weaning and examined its effect on renal function parameters during their adulthood. The animals were divided into four groups of 5-10 rats in each group: control, control supplemented with fish oil (P), cachectic Walker 256 tumor-bearing (W), and W supplemented with fish oil (WP). Food intake was significantly lower in the W group compared to control (12.66 ± 4.24 vs 25.30 ± 1.07 g/day). Treatment with fish oil significantly reversed this reduction (22.70 ± 2.94 g/day). Tumor growth rate... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fish oil supplementation; Renal function; Cachexia; Walker 256 tumor; Sodium excretion; Glomerular filtration rate. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004001000006 Registros recuperados: 3 Primeira ... 1 ... Última

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