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Radiation Nephritis: Anti-inflammatory Effect of Dexamethasone in Adult Wistar Rats (Rattus norvegicus) International Journal of Morphology
Owoeye,O; Malomo,A. O; Elumelu,T. N; Salami,A. A; Osuagwu,F. C; Akinlolu,A. A; Adenipekun,A; Shokunbi,M. T.
The anti-inflammatory effect of dexamethasone on the irradiated kidneys of adult Wistar rats (Rattus norvegicus) was studied. Eighteen adult Wistar rats were, after acclimatization, randomly divided into 3 groups of 6 animals per group. The control group had normal saline, receiving neither drugs nor radiation. The second group received normal saline and radiation. The third group received pretreatment with dexamethasone at 1mg/kg body weight/day for 2 days followed by radiation. Radiation was delivered to the animals as a single fraction of 2.5 Gy of gamma rays from Cobalt-60 source, using an AECL Theatron 780-C Teletherapy machine. After exposure to the different interventions, the animals were sacrificed on the 14th post-irradiation day and the kidneys...
Tipo: Journal article Palavras-chave: Radiation; Nephrons; Glomerulus; Nephritis; Anti-inflammatory; Kidney.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000100011
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Anomalies, Aneurysm and Histology of the Middle Cerebral Artery in Nigerian Africans International Journal of Morphology
Idowu,O. E; Shokunbi,M.T; Malomo,A. O; Akang,E. E. U.
The histology of the middle cerebral artery (MCA) in Nigerian Africans has not been previously studied. One hundred MCAs obtained at autopsy from fifty adult Nigerians were studied. The vessels were processed and stained with Ehrlich's haematoxylin and eosin, elastic Van Gieson and Masson's trichrome stains. Early branches were given off before the perforators in two middle cerebral arteries, and there was one accessory MCA, making an incidence of anomalies of 3%. No aneurysm was observed in any of the cases. The internal elastic laminas were well developed but the external elastic laminas of the vessels were poorly developed. Cióse to the bif urcations the túnica media tapered gradually and at the bif urcations, the túnica media was completely deficient...
Tipo: Journal article Palavras-chave: Anomalies; Histology; Middle cerebral artery.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400038
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