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| Malomo,A. O.; Ekpo,O. E.; Imosemi,I. O.; Owoeye,O.; Osuagwu,F. C.; Avwioro,O. G.; Shokunbi,M.T.. |
| The neuroprotective effect of dexamethasone on the irradiated postnatal developing cerebellum of Wistar rat was studied. Seventy-five (day 1 old) neonates were separated into three groups; control group receiving no drug and no irradiation, irradiated group, and irradiated and dexamethasone group in which the dexamethasone was administered one hour before exposure to 5Gray (5Gy) of gamma rays. On complete exposure to the various interventions, the cerebellar tissues of animals from each group on days 5, 9, 14, 21 and 25 were processed for histological and histomorphometric studies. The result of the study showed that irradiation alone significantly reduced the thickness of the external granular layer (EGL) on day 5 and 14 at P<0.05, molecular layer (ML)... |
| Tipo: Journal article |
Palavras-chave: Morphology; Irradiation; Dexamethasone; Developing cerebellum. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000300017 |
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