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Mamun,Md. Abdullah Al; Hosen,Mohammad Jakir; Islam,Kamrul; Khatun,Amina; Masihul Alam,M.; Al-Bari,Md. Abdul Alim. |
BACKGROUND: Tridaxprocumbens flavonoids (TPFs) are well known for their medicinal properties among local natives. Besides traditionally used for dropsy, anemia, arthritis, gout, asthma, ulcer, piles, and urinary problems, it is also used in treating gastric problems, body pain, and rheumatic pains of joints. TPFs have been reported to increase osteogenic functioning in mesenchymal stem cells. Our previous study showed that TPFs were significantly suppressed the RANKL-induced differentiation of osteoclasts and bone resorption. However, the effects of TPFs to promote osteoblasts differentiation and bone formation remain unclear. TPFs were isolated from Tridax procumbens and investigated for their effects on osteoblasts differentiation and bone formation by... |
Tipo: Journal article |
Palavras-chave: Alkaline phosphatase; Bone formation; Osteoblast differentiation; Osteocalcin. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100065 |
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Mamun,Md. Abdullah Al; Islam,Kamrul; Alam,Md. Jahangir; Khatun,Amina; Masihul Alam,M; Al-Bari,Md. Abdul Alim; Alam,Md. Jahangir. |
BACKGROUND: The Tridax procumbens flavonoids (TPF), are well known for their medicinal properties among local natives. The TPF are traditionally used for dropsy, anaemia, arthritis, gout, asthma, ulcer, piles, and urinary problems. It also used in treating gastric problems, body pain, and rheumatic pains of joints. The TPF have been reported to increase osteogenic functioning in mesenchymal stem cells. However, their effects on osteoclastogenesis remain unclear. The TPF isolated from T. procumbens and investigated the effects of the TPF inhibit on osteoclast differentiation and bone resorption activities using primary osteoclastic cells. Osteoclast formation was assessed by counting the number of tartrate resistant acid phosphatase (TRAP) positive... |
Tipo: Journal article |
Palavras-chave: Bone resorption; Osteoclast differentiation; Pit formation; TRAP positive cells. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100051 |
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