|
|
| Manso,P.H.; Figueira,R.L.; Prado,C.M.; Gonçalves,F.L.; Simões,A.L.B.; Ramos,S.G.; Sbragia,L.. |
| This study aimed to demonstrate that congenital diaphragmatic hernia (CDH) results in vascular abnormalities that are directly associated with the severity of pulmonary hypoplasia and hypertension. These events increase right ventricle (RV) afterload and may adversely affect disease management and patient survival. Our objective was to investigate cardiac function, specifically right ventricular changes, immediately after birth and relate them to myocardial histological findings in a CDH model. Pregnant New Zealand rabbits underwent the surgical procedure at 25 days of gestation (n=14). CDH was created in one fetus per horn (n=16), and the other fetuses were used as controls (n=20). At term (30 days), fetuses were removed, immediately dried and weighed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Congenital diaphragmatic hernia; Right ventricle; Pulmonary arterial hypertension; Echocardiography. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000300234 |
| |
