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| Pedrotti, Ml; Marchi, B; Lemee, R. |
| The biological activity of a methanolic extract of the introduced species Caulerpa taxifolia and caulerpenyne (main secondary metabolite of the alga) was tested on embryogenesis, pluteus and metamorphosis stages of the sea urchin Paracentrotus lividus. The bioassays revealed different levels of toxicity according to the egg and larval development stages. Larval development was the most sensitive phase, followed by gastrulation. Methanolic extracts at a concentration of 1.0 mu g ml(-1) and caulerpenyne at a concentration of 100 ng ml(-1) (300 nM) tested on young larvae (4-arm stage) cause death within four hours. The same concentrations of methanolic extract, tested on eggs, blocked cleavage up to early blastula stage, whereas a double concentration of... |
| Tipo: Text |
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| Ano: 1996 |
URL: http://archimer.ifremer.fr/doc/00094/20484/18154.pdf |
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| Marchi, B; Trielli, F; Falugi, C; Corre, Mc; Fenaux, L. |
| Cell-to-cell and cell-environment interactions are known to play a role during the first events of sea urchin development. Larval metamorphosis in benthic invertebrates is induced by environmental signals (cues), received by membrane receptors. The activity of such cues may be disturbed by the presence of toxic agents from pollution. We consider the possibility that neurotransmitter receptor-like molecules may have a role in the regulation of larval development and metamorphosis. To investigate the effects exerted on these processes by neuroactive pollutants, such as neurotoxic insecticides, we tested the function of acetylcholine receptors (muscarinic acetylcholine receptors mAChR and nicotinic acetylcholine receptors nAChR) in larvae of Paracentrotus... |
| Tipo: Text |
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| Ano: 1996 |
URL: http://archimer.ifremer.fr/doc/00096/20747/18376.pdf |
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