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Effect of alcoholic beverages on progeny and reproduction of mice BJPS
Figueiro,Fernanda Dias; Bispo,Ana Clara Cerato; Guarido,Karla Lorena; Marianno,Priscila; Costa,Gabriel de Araújo; Morimoto,Helena Kaminami; Salles,Maria José Sparça.
ABSTRACT Alcohol is the most commonly consumed substance in the world. The objective of this study was to evaluate the influence of alcoholic beverages on male reproduction and possible alterations in their offspring. The mice were divided into 4 groups: beer, wine, cachaça (a type of sugarcane rum), with ethanol concentrations of 1.9 g/kg, and control group treated with PBS. The treatment period was 35 days. The animals which received cachaça, demonstrated significant weight loss in the testes and epididymis. The alcoholic beverages promoted significant testosterone level and fertilization index diminution, and morphological alterations in the spermatozoa. The beer group presented decreased implantation sites and a high frequency of dominant lethal. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Alcoholic beverages/analysis; Wine/adverse effects; Beer/adverse effects; Cachaça/adverse effects; Reproduction/drugs effects.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400612
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