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	Provedor de dados Anais da ABC (AABC) (2) Autor Marques Jr.,Ernesto T.A. (2) Acioli-Santos,Bartolomeu (1) August,Thomas (1) Calzavara-Silva,Carlos E. (1) Cruz,Fábia S.P. (1) Dhalia,Rafael (1) Gil,Laura H.V.G. (1) Gomes,Ana L.V. (1) Maciel Jr.,Milton (1) Maia,Rita C.C. (1) Palma,Mariana L. (1) Viana,Isabelle F.T. (1) Mais... Palavra-chave DNA vaccines (1) Dengue (1) Dengue hemorrhagic fever (1) Lysosome-Associated Membrane Protein - LAMP (1) Molecular markers (1) Real-time PCR (1) West Nile (1) Yellow fever (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2009 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Early molecular markers predictive of dengue hemorrhagic fever Anais da ABC (AABC) Calzavara-Silva,Carlos E.; Gomes,Ana L.V.; Maia,Rita C.C.; Acioli-Santos,Bartolomeu; Gil,Laura H.V.G.; Marques Jr.,Ernesto T.A.. The management of acute dengue patients during outbreaks is a challenging problem. Most of the dengue fever cases are benign, but some cases develop into a severe and possibly lethal vasculopathy, known as dengue hemorrhagic fever. Early symptoms of dengue and hemorrhagic fever are very similar. An early differential diagnosis is needed to predict which of these two clinical presentations is crucial to proper patient care and public health management. This study evaluates the predictive potential of specific mRNA expression markers of dengue hemorrhagic fever using quantitative real-time PCR assays. Six candidate "dengue hemorrhagic fever specific signature genes" were evaluated and all showed good correlation among their transcription levels at early days... Tipo: Info:eu-repo/semantics/article Palavras-chave: Real-time PCR; Dengue hemorrhagic fever; Molecular markers. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000400006 Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses Anais da ABC (AABC) Dhalia,Rafael; Maciel Jr.,Milton; Cruz,Fábia S.P.; Viana,Isabelle F.T.; Palma,Mariana L.; August,Thomas; Marques Jr.,Ernesto T.A.. Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even rare fatal reactions. Given this scenario, the developent of alternative vaccination strategies such as DNA-based vaccines encoding specific flavivirus sequences are being considered. Endogenous cytoplasmic antigens, characteristically plasmid DNA-vaccine encoded, are mainly presented to the immune system through Major Histocompatibility Complex class I - MHC I molecules. The MHC I presentation via is mostly associated with a cellular cytotoxic response and often do not elicit a satisfactory humoral... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dengue; West Nile; Yellow fever; Lysosome-Associated Membrane Protein - LAMP; DNA vaccines. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652009000400005 Registros recuperados: 2 Primeira ... 1 ... Última

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