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	Provedor de dados BJMBR (2) Autor Massirer,K.B. (2) Durham,A.M. (1) Ferraz,M.L.G. (1) Ferreira,C.E. (1) Fujita,A. (1) Hirata,M.H. (1) Hirata,R.D.C. (1) Nguyen,N.Y. (1) Silva,A.E.B. (1) Sogayar,M.C. (1) Mais... Palavra-chave (GATO) (1) Automatic annotation (1) Bioinformatics (1) Chronic hepatitis C (1) Gene annotation tool (1) IFNAR1-mRNA expression (1) Interferon-alpha receptor (1) Interferon-alpha therapy (1) Peripheral blood mononuclear cells (1) Pipeline (1) Reverse transcription- polymerase chain reaction (1) Mais... Tipo do documento Info:eu-repo/semantics/other (2) Ano 2005 (1) 2004 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última The GATO gene annotation tool for research laboratories BJMBR Fujita,A.; Massirer,K.B.; Durham,A.M.; Ferreira,C.E.; Sogayar,M.C.. Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research. Here we present an automatic annotation system for preliminary analysis of DNA sequences. The gene annotation tool (GATO) is a Bioinformatics pipeline designed to facilitate routine functional annotation and easy access to annotated genes. It was designed in view of the frequent need of genomic researchers to access data pertaining to a common set of genes. In the GATO system, annotation is generated by querying some of the Web-accessible resources and the information is stored in a local database, which keeps a record of all previous... Tipo: Info:eu-repo/semantics/other Palavras-chave: Gene annotation tool; (GATO); Automatic annotation; Pipeline; Bioinformatics. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100002 Interferon-alpha receptor 1 mRNA expression in peripheral blood mononuclear cells is associated with response to interferon-alpha therapy of patients with chronic hepatitis C BJMBR Massirer,K.B.; Hirata,M.H.; Silva,A.E.B.; Ferraz,M.L.G.; Nguyen,N.Y.; Hirata,R.D.C.. Interferon (IFN)-alpha receptor mRNA expression in liver of patients with chronic hepatitis C has been shown to be a response to IFN-alpha therapy. The objective of the present study was to determine whether the expression of mRNA for subunit 1 of the IFN-alpha receptor (IFNAR1) in peripheral blood mononuclear cells (PBMC) is associated with the response to IFN-alpha in patients with chronic hepatitis C. Thirty patients with positive anti-HCV and HCV-RNA, and abnormal levels of alanine aminotransferase in serum were selected and treated with IFN-alpha2b for one year. Those with HBV or HIV infection, or using alcohol were not included. Thirteen discontinued the treatment and were not evaluated. The IFN-alpha response was monitored on the basis of alanine... Tipo: Info:eu-repo/semantics/other Palavras-chave: IFNAR1-mRNA expression; Interferon-alpha therapy; Chronic hepatitis C; Interferon-alpha receptor; Peripheral blood mononuclear cells; Reverse transcription- polymerase chain reaction. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000500003 Registros recuperados: 2 Primeira ... 1 ... Última

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