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| Matsumoto,Silvia Tamie; Mantovani,Mário Sérgio; Malaguttii,Mirtis Irene Ariza; Dias,Ana Lúcia; Fonseca,Inês Cristina; Marin-Morales,Maria Aparecida. |
| Cytotoxicity of metals is important because some metals are potential mutagens able to induce tumors in humans and experimental animals. Chromium can damage DNA in several ways, including DNA double strand breaks (DSBs) which generate chromosomal aberrations, micronucleus formation, sister chromatid exchange, formation of DNA adducts and alterations in DNA replication and transcription. In our study, water samples from three sites in the Córrego dos Bagres stream in the Franca municipality of the Brazilian state of São Paulo were subjected to the comet assay and micronucleus test using erythrocytes from the fish Oreochromis niloticus. Nuclear abnormalities of the erythrocytes included blebbed, notched and lobed nuclei, probably due to genotoxic chromium... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Allium cepa; Chromium; Chromosomes aberrations; Comet assay; Micronucleus; Oreochromis niloticus. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000100028 |
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| Malini,Maressa; Marin-Morales,Maria Aparecida; Mantovani,Mário Sérgio; Jamal,Claudia Masrouah; Nati,Natália; Passos,Tatiane da Silva; Matsumoto,Silvia Tamie. |
| An aqueous extract of Rhizophora mangle L. bark is used as raw material in pottery making in the State of Espirito Santo, Brazil. This extract presents large quantities of tannins, compounds possessing antioxidant properties. Tannin antioxidant activity, as a plant chemical defense mechanism in the process of stabilizing free radicals, has been an incentive to studies on anti-mutagenicity. The present work aimed to evaluate possible antimutagenic activity of a R. mangle aqueous extract, using the Allium cepa test-system and micronuclear (MN) assay with blockage of cytokinesis in Chinese hamster ovary cells (CHO-K1). The Allium cepa test-system indicated antimutagenic activity against the damage induced by the mutagenic agent methyl methanesulfonate. A... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rhizophora mangle; Antimutagenicity; Allium cepa; CHO-K1. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000100029 |
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| Machado,Levi Pompermayer; Matsumoto,Silvia Tamie; Cuzzuol,Geraldo Rogério Faustini; Oliveira Jr,Luiz Fernando Ganassali. |
| The present study examined changes that took place in the physiology of three species of Rhodophyta by analysing the concentration of pigments and non-structural carbohydrates, comparatively evaluating algae collected from nature and after 28 days of laboratory cultivation. Another objective of the study was to determine whether the species retain their antifungal potential after the period of laboratory cultivation, correlating the changes in physiology and those from bioactivity. After carrying out laboratory cultivation, the results indicated a trend, in the three species of macroalgae, towards a reduction in pigment concentrations, mainly in the phycobiliproteins. For the non-structural carbohydrates no response pattern of the macroalgae was observed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plant physiology; Macroalgae; Nonstructural carbohydrates; Pigments. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-66902014000100007 |
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