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International Journal of Morphology (1)

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	Antioxidant (1)
	Melatonin (1)
	Mouse sperm (1)
	Organophosphates (1)
	Sperm morphology (1)

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Journal article (1)

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2011 (1)

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Protective Effect of Melatonin on Damage in the Sperm Parameters of Mice Exposed to Diazinon

International Journal of Morphology

Sarabia,L; Espinoza-Navarro,O; Maurer,I; Ponce,C; Bustos-Obregón,E.

Since normal sperm parameters can be altered by organophosphorous pesticides, this study intended to determine if melatonin is able to prevent the damage on sperm quality after an acute exposure to diazinon. Adult male mice were injected intraperitoneally with melatonin, diazinon (1/3 or 2/3 LD50) or both, and sperm parameters were evaluated on days 1 or 32 post injection. Groups treated with diazinon showed elevated lipid peroxidation levels on day 1 post treatment, while groups pretreated with melatonin before diazinon showed no difference compared to control. Sperm count showed a significant decrease in both diazinon-treated groups only on day 32 post injection; no differences were observed in groups pretreated with melatonin prior to diazinon compared...

Tipo: Journal article

Palavras-chave: Melatonin; Organophosphates; Antioxidant; Mouse sperm; Sperm morphology.

Ano: 2011

URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400029

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