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	Provedor de dados BJMBR (1) Autor Bulhões,A.C. (1) Goldani,H.A.S. (1) Matte,U.S. (1) Mazzuca,R.B. (1) Oliveira,F.S. (1) Silveira,T.R. (1) Mais... Palavra-chave Hydrogen breath test (1) LCT polymorphism (1) Lactase-phlorizin hydrolase (1) Lactose intolerance (1) Milk intolerance (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2007 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia BJMBR Bulhões,A.C.; Goldani,H.A.S.; Oliveira,F.S.; Matte,U.S.; Mazzuca,R.B.; Silveira,T.R.. The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910. The objective of the present study was to assess the presence of these two mutations in Brazilian individuals with and without lactose malabsorption diagnosed by the hydrogen breath test (HBT). Ten milk-tolerant and 10 milk-intolerant individuals underwent the HBT after oral ingestion of 50 g lactose (equivalent to 1 L of milk). Analyses for C/T-13910 and G/A-22018 mutations were performed using a PCR-based method. Primers were designed for this study based on the GenBank sequence. The CT/GA, CT/AA, and TT/AA genotypes (lactase persistence) were found in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hydrogen breath test; Lactase-phlorizin hydrolase; Lactose intolerance; Milk intolerance; LCT polymorphism. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007001100004 Registros recuperados: 1 Primeira ... 1 ... Última

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