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| Silva,L.A.; Felipe,C.R.; Park,S.I.; Pinheiro-Machado,P.; Garcia,R.; Franco,M.; Moreira,S.R.; Tedesco-Silva Jr.,H.; Medina-Pestana,J.. |
| We conducted a retrospective analysis of the influence of full doses of calcineurin inhibitors [8-10 mg kg-1 day-1 cyclosporine (N = 80), or 0.2-0.3 mg kg-1 day-1 tacrolimus (N = 68)] administered from day 1 after transplantation on the transplant outcomes of a high-risk population. Induction therapy was used in 13% of the patients. Patients also received azathioprine (2 mg kg-1 day-1, N = 58) or mycophenolate mofetil (2 g/day, N = 90), and prednisone (0.5 mg kg-1 day-1, N = 148). Mean time on dialysis was 79 ± 41 months, 12% of the cases were re-transplants, and 21% had panel reactive antibodies >10%. In 43% of donors the cause of death was cerebrovascular disease and 27% showed creatinine above 1.5 mg/dL. The incidence of slow graft function (SGF) and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cyclosporine; Tacrolimus; Delayed graft function; Graft function; Kidney transplantation. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100005 |
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