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Prevalence, risk factors and genotypes of hepatitis B infection among HIV-infected patients in the State of MS, Central Brazil BJID
Freitas,Solange Zacalusni; Soares,Caroline Cordeiro; Tanaka,Tayana Serpa Ortiz; Lindenberg,Andréa Siqueira Campos; Teles,Sheila Araújo; Torres,Marina Sawada; Mello,Francisco Campello Amaral; Mendes-Corrêa,Maria Cássia; Savassi-Ribas,Flávia; Motta-Castro,Ana Rita Coimbra.
Objectives:A cross-sectional study on prevalence of HBV and HDV infection, risk factors and genotype distribution of HBV infection was conducted among 848 HIV-infected patients in Mato Grosso do Sul, Central Brazil.Methods:Serum samples of 848 participants were tested for hepatitis B surface antigen (HBsAg), hepatitis B core antibody (anti-HBc) and hepatitis surface antibody (anti-HBs). HBsAg positive samples were tested for anti-HBc IgM, HBeAg, anti-HBe, anti-HCV, and total anti-HDV. HBsAg and anti-HBc positive were subjected to DNA extraction. Viral DNA was amplified by semi-nested PCR for the regions pre-S/S and then purified and genotyped/subgenotyped by direct sequencing. Student's t-test, chi-square test and Fisher's exact test were used to compare...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coinfection; HBV; HIV; Prevalence.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500473
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