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| Colpo,A.C.; Lima,M.E.; da Rosa,H.S.; Leal,A.P.; Colares,C.C.; Zago,A.C.; Salgueiro,A.C.F.; Bertelli,P.R.; Minetto,L.; Moura,S.; Mendez,A.S.L.; Folmer,V.. |
| Studies have suggested that total energy intake and diet composition affect lifespan and ageing. A high-fat diet induces oxidative stress and affects the development of diseases. In contrast, antioxidants are capable of reducing its harmful effects. Yerba mate beverages are an important source of antioxidants, but there is scarce knowledge about their effects on suppressing fat accumulation. Here, we investigated the compounds present in yerba mate extracts and assessed their effects on Drosophila melanogaster given a high cholesterol diet. LS-ESI-MS analysis showed the presence of matesaponins, phenolic compounds and methylxanthines in all of the examined extracts. In Drosophila, under extract treatment conditions, the mean lifespan was significantly... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Yerba mate; Matesaponin; LC-MS; Antioxidants compounds; Chronic diseases; Oxidative stress. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000200601 |
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| da Rosa,H.S.; Salgueiro,A.C.F.; Colpo,A.Z.C.; Paula,F.R.; Mendez,A.S.L.; Folmer,V.. |
| Sida tuberculata (Malvaceae) is a medicinal plant traditionally used in Brazil as an antimicrobial and anti-inflammatory agent. Here, we aimed to investigate the different extractive techniques on phytochemical parameters, as well as to evaluate the toxicity and antioxidant capacity of S. tuberculata extracts using in silico and in vitro models. Therefore, in order to determine the dry residue content and the main compound 20-hydroxyecdysone (20E) concentration, extracts from leaves and roots were prepared testing ethanol and water in different proportions. Extracts were then assessed by Artemia salina lethality test, and toxicity prediction of 20E was estimated. Antioxidant activity was performed by DPPH and ABTS radical scavenger assays, ferric reducing... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sida tuberculata; 20-hydroxyecdysone; Toxicity prediction; Antioxidant. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000800602 |
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