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| Braga-Silva,L.A.; Mesquita,D.G.A.; Ribeiro,M.D.; Carvalho,S.M.F.; Fracalanzza,S.E.L.; Santos,A.L.S.. |
| Candida albicans is an opportunistic fungal pathogen that causes severe systemic infections in immunosuppressed individuals. C. albicans resistance to antifungal drugs is a severe problem in patients receiving prolonged therapy. Moreover, trailing yeast growth, which is defined as a resistant MIC after 48 h of incubation with triazole antifungal agents but a susceptible MIC after 24 h, has been noted in tests of antifungal susceptibility against some C. albicans isolates. In this context, we recently noticed this phenomenon in our routine susceptibility tests with fluconazole/itraconazole and C. albicans clinical isolates. In the present study, we investigated the production of cell-associated and secreted aspartyl peptidases (Saps) in six trailing... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida albicans; Trailing growth; Secreted aspartyl peptidases; Sap2. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000800013 |
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