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Fetal hemoglobin levels are related to metabolic control in diabetic subjects BJMBR
Pardini,V.C.; Victória,I.M.N.; Pieroni,F.B.; Milagres,G.; Nascimento,P.D.; Velho,G.; Purisch,S.; Pardini,H..
We have investigated the relationship between fetal hemoglobin (HbF) levels and metabolic control in subjects with insulin-dependent (N = 79) and non-insulin-dependent diabetes mellitus (N = 242). HbF and hemoglobin A1c (HbA1c) levels were increased in subjects with type 1 and type 2 diabetes as compared to levels in nondiabetic individuals (P<0.0001), and were significantly higher in type 1 than in type 2 diabetes subjects. Lower levels of HbA1c and HbF were observed in type 2 diabetes subjects treated by diet, intermediate levels in those treated with oral hypoglycemic agents, and higher levels in those treated with insulin. HbF and HbA1c levels were correlated in type 1 diabetes (R2 = 0.57, P<0.0001) and type 2 diabetes (R2 = 0.58,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fetal hemoglobin; HbA1c; Glycated hemoglobin; Diabetes mellitus; Type 1 diabetes; Type 2 diabetes.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000600005
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